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Article

S-PrediXcan predicted gene expression in human placenta is associated with childhood-onset asthma risk.

Scientific reports - 13 May 2026

Jasper Elizabeth A, McKennan Christopher G, Thompson Emma E, Schoettler Nathan, Gebretsadik Tebeb, Hellwege Jacklyn N, Edwards Todd L, Ober Carole, Velez Edwards Digna R, Hartert Tina V, Snyder Brittney M

Abstract excerpt

Investigation of in utero, tissue-specific molecular pathways contributing to prenatal programming of childhood-onset asthma is needed to develop effective, targeted prevention strategies. We aimed to examine the relationship between predicted gene expression in placenta and childhood-onset asthma and to compare relationships between childhood- and adult-onset asthma. Asthma genome-wide association study...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42129325
DOI: 10.1038/s41598-026-51718-1
PMCID: PMC13365522

Genes

ACTL9
AMN
CTSE
EFCAB13
EIF4E1B
FN1
GLS2
IL6
IVL
LZIC
MAN2A2
RACGAP1
SMAD6
TMEM25
VTI1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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