Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.

Placenta - 22 May 2026

Akerele Alexis T, Hampton Gabrielle, Kim Jeewoo, Jaworski James, Lewis Toni J, Khan Atlas, Rasmussen-Torvik Laura J, Luo Yuan, Jasper Elizabeth A, Hellwege Jacklyn N, Edwards Todd L, Velez Edwards Digna R

Abstract excerpt

INTRODUCTION: Mother-to-child disease transmission begins in utero, with the placenta playing a critical role in pregnancy and offspring health. Uterine leiomyomata (fibroids, UFs) and endometriosis (ENDO) are common gynecologic diseases that have substantial overlaps in symptomology and risk factors, however drivers of disease risk remain unclear. The objective of this study was to investigate shared placental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometriosis
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Leiomyoma

Share to Placenta

Share to Pregnancy

Share to Uterine Neoplasms

Source

Identifiers

PMID: 41936293
DOI: 10.1016/j.placenta.2026.03.023

Genes

HRH1
PRKCI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.PMID 41936293Read ↗

Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid.Semantic proximity Read ↗

Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases.Semantic proximity Read ↗

Association of genetically-predicted placental gene expression with adult blood pressure traits.Semantic proximity Read ↗

Placental expression quantitative trait loci in an East Asian population.Semantic proximity Read ↗

Evolution of the genetic architecture of uterine disordersSemantic proximity Read ↗

A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypesSemantic proximity Read ↗

Current knowledge on genetic variants shaping placental transcriptome and their link to gestational and postnatal health.Semantic proximity Read ↗

Genome-wide maps of distal gene regulatory regions active in the human placentaSemantic proximity Read ↗

Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.Semantic proximity Read ↗

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.Semantic proximity Read ↗

A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypesSemantic proximity Read ↗

Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.