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Article

miR-206 regulates hypoxia-induced mitophagy and phenotypic remodeling in yak pulmonary artery smooth muscle cells.

Molecular biology of the cell - 1 Jun 2026

Zhao Pengfei, Yang Shanshan, Wei Pengqiang, Li Shijie, He Junfeng, Cui Yan, Yu Sijiu

Abstract excerpt

Hypoxia drives pulmonary artery smooth muscle cells (PASMCs) proliferation and phenotypic remodeling, processes central to vascular adaptation. Yaks, native to high-altitude environments, provide a natural model for studying cellular responses to chronic hypoxia. In this study, hypoxic exposure enhanced yak PASMCs' proliferation and induced phenotypic transformation. Transcriptome profiling revealed that hypoxia...

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Share to Cell Hypoxia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

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Source

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Identifiers

PMID: 42126961
DOI: 10.1091/mbc.E25-11-0529
PMCID: PMC13329810

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BNIP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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