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Article

Artemisinin partial resistance at a crossroads: evidence for continental variation in Plasmodium falciparum clearance phenotypes.

The Lancet. Infectious diseases - 1 Sept 2026

Hosangadi Varun, Fidock David A

Abstract excerpt

Artemisinin-based combination therapies (ACTs) remain the cornerstone of global malaria treatment, yet their long-term efficacy is threatened by the emergence of artemisinin partial resistance (ART-R). Current surveillance definitions rely on Plasmodium falciparum parasite clearance half-life thresholds derived from southeast Asia, where mutant kelch13 (k13)-mediated resistance produces prolonged parasite...

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PMID: 42107390
DOI: 10.1016/S1473-3099(26)00132-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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