Article
Profiles of Kelch mutations in Plasmodium falciparum across South Asia and their implications for tracking drug resistance
4 Oct 2019
Abstract excerpt
Artemisinin-based combination therapy (ACT) offers highly successful treatment of malaria. Emergence and spread of Plasmodium falciparum (Pf) parasites with decreased susceptibility to ACT in South-East Asia has caused concern worldwide. The current accepted criteria to assess artemisinin (ART) resistance relies upon data on treatment failure, delayed parasite clearance at day 3 (DPC3), parasite clearance...
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