Article
Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis
8 Dec 2017
Abstract excerpt
metastatic PCa, multiplatform single cell profiling was performed using high definition single cell analysis (HD-SCA). HD-SCA enabled morphoproteomic and morphogenomic profiling of single cells from touch preparations of tissue cores (prostate and bone marrow biopsies) as well as liquid samples (peripheral blood and bone marrow aspirate). Morphology, nuclear features, copy number alterations, and protein...
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