Article

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis

2018-05-11

Abstract excerpt

<h4>Background</h4> There are multiple existing and emerging therapeutic avenues for metastatic prostate cancer, with a common denominator, which is the need for predictive biomarkers. Circulating tumor DNA (ctDNA) has the potential to cost-efficiently accelerate precision medicine trials to improve clinical efficacy and diminish costs and toxicity. However, comprehensive ctDNA profiling in metastatic prostate ca...

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Literature Corpus work: 8ac5b1a1-a996-57c1-ad60-5ea219036fe8
DOI: 10.1101/319855

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