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Article

Molecular insights into the mechanisms of occult hepatitis B virus infection.

Archives of virology - 7 May 2026

Mahdavi Sina, Abyazi Mohammad Ali, Gouvarchin Ghaleh Hadi Esmaeili, Golmohammadi Reza, Salimi Jeda Ali

Abstract excerpt

Occult hepatitis B virus Infection (OBI) is a form of hepatitis B virus (HBV) persistence that is not accompanied by the presence of circulating HBsAg. It is generally defined as the presence of replication-competent viral DNA, mostly covalently closed circular DNA (cccDNA), in hepatocytes. Although viral load is low and serum markers are typically undetectable, OBI has clinical significance due to its...

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Share to DNA, Circular
Share to DNA, Viral
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B

Share to Hepatitis B virus

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Share to Immune Evasion

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Identifiers

PMID: 42096075
DOI: 10.1007/s00705-026-06639-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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