Molecular testing in the diagnosis and management of chronic hepatitis B.

doi:10.1128/CMR.00009-07

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Article

Molecular testing in the diagnosis and management of chronic hepatitis B.

Clinical microbiology reviews - 1 Jul 2007

Valsamakis Alexandra

Abstract excerpt

Hepatitis B virus (HBV) is an enveloped virus with a small (3.2-kb) partially double-stranded DNA genome that causes acute and chronic infections. The impact of these infections on public health worldwide is enormous, with an estimated prevalence of 2 billion acute infections and 360 million chronic infections globally. This review focuses on chronic hepatitis B and the molecular assays used in its diagnosis and...

Topics

Antiviral Agents
DNA Mutational Analysis
DNA, Viral
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Nucleic Acid Amplification Techniques
Phenotype
Polymerase Chain Reaction
Promoter Regions, Genetic
Species Specificity

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Identifiers

PMID: 17630333
DOI: 10.1128/CMR.00009-07
PMCID: PMC1932755

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