Article
The virological aspects of hepatitis B.
Best practice & research. Clinical gastroenterology - 1 Jun 2017
Valaydon Zina S, Locarnini Stephen A
Abstract excerpt
Human hepatitis B virus (HBV) is a hepatotropic virus that is responsible for a significant burden of disease, causing liver disease and hepatocellular carcinoma. It is a small DNA virus with a replication strategy that is similar to that of a retrovirus. HBV is prone to mutagenesis and under the influence of diverse selection pressures, has evolved into a pool of quasispecies, genotypes and mutants, which...
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