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Interactions between dietary patterns and genetic factors in relation to incident dementia among 70-year-olds.

European journal of nutrition - 1 Mar 2022

Samuelsson Jessica, Najar Jenna, Wallengren Ola, Kern Silke, Wetterberg Hanna, Mellqvist Fässberg Madeleine, Zetterberg Henrik, Blennow Kaj, Lissner Lauren, Rothenberg Elisabet, Skoog Ingmar, Zettergren Anna

Abstract excerpt

PURPOSE: To investigate potential interactions between dietary patterns and genetic factors modulating risk for Alzheimer's disease (AD) in relation to incident dementia. METHODS: Data were derived from the population-based Gothenburg H70 Birth Cohort Studies in Sweden, including 602 dementia-free 70-year-olds (examined 1992-93, or 2000-02; 64% women) followed for incident dementia until 2016. Two factors from a...

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Alzheimer Disease
Apolipoprotein E4
Genotype
Heterozygote
Proportional Hazards Models

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PMID: 34632537
DOI: 10.1007/s00394-021-02688-9
PMCID: PMC8854136

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