The shortest known prion protein gene allele occurs in goats, has only three octapeptide repeats and is non-pathogenic.

doi:10.1099/0022-1317-79-12-3173

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Article

The shortest known prion protein gene allele occurs in goats, has only three octapeptide repeats and is non-pathogenic.

The Journal of general virology - 1 Dec 1998

Goldmann W, Chong A, Foster J, Hope J, Hunter N

Abstract excerpt

The prion protein (PrP) gene modulates the incidence and incubation periods of transmissible spongiform encephalopathies of sheep, goats, mice and man. Here, a new caprine PrP allele encoding the shortest naturally occurring PrP protein so far described is reported. This variant contains only thr...

Topics

Alleles
Animals
Goats
Oligopeptides
Prions

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