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Article

Biomarker Variants of Dopamine Receptor Genes Influence the Binding Interaction Between Dopamine Receptor and Risperidone.

Drug design, development and therapy - 1 Jan 2026

Almandil Noor B, AbdulAzeez Sayed, Gomaa Mohamed S, Ibrahim Abdallah M, John Sherlin John, Prathas Selvaraj, Dhas Tharmathass Stalin, Borgio Jesu Francis

Abstract excerpt

Introduction: Risperidone is atypical antipsychotic medication commonly used to control behavioral symptoms in children with autism and widely considered a first-line treatment for acute and maintenance treatment of schizophrenia and bipolar mania. However, the response to risperidone is varied between patients due to genetic factors such as dopamine receptor genes. Methods: Using state-of-the-art tools, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42052100
DOI: 10.2147/DDDT.S587705
PMCID: PMC13117852

Genes

DRD2
DRD1
DRD3
DRD4
DRD5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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