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Article

Investigating the structural impact of S311C mutation in DRD2 receptor by molecular dynamics & docking studies.

Biochimie - 1 Apr 2016

Podder Avijit, Pandey Deeksha, Latha N

Abstract excerpt

Dopamine receptors (DR) are neuronal cell surface proteins that mediate the action of neurotransmitter dopamine in brain. Dopamine receptor D2 (DRD2) that belongs to G-protein coupled receptors (GPCR) family is a major therapeutic target for of various neurological and psychiatric disorders in human. The third inter cellular loop (ICL3) in DRD2 is essential for coupling G proteins and several signaling scaffold...

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Source

Identifiers

PMID: 26805384
DOI: 10.1016/j.biochi.2016.01.011

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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