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A comprehensive <i>in silico</i> investigation into the nsSNPs of <i>Drd2</i> gene predicts significant functional consequences in dopamine signaling and pharmacotherapy

2021-06-11

Abstract excerpt

DRD2 is a neuronal cell surface protein involved in brain development and function. Variations in the Drd2 gene have clinical significance since DRD2 is a pharmacotherapeutic target for treating psychiatric disorders like ADHD and schizophrenia. Despite numerous studies on the disease association of single nucleotide polymorphisms (SNPs) in the intronic regions, investigation into the coding regions is surprising...

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Literature Corpus work
0eadab74-d8f3-52ea-9576-33f99f41f542
DOI
10.1101/2021.06.11.448090
Open publication

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A comprehensive <i>in silico</i> investigation into the nsSNPs of <i>Drd2</i> gene predicts significant functional consequences in dopamine signaling and pharmacotherapyDOI 10.1101/2021.06.11.448090
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