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Article

Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia.

Pharmacogenomics - 1 Oct 2008

Ikeda Masashi, Yamanouchi Yoshio, Kinoshita Yoko, Kitajima Tsuyoshi, Yoshimura Reiji, Hashimoto Shuji, O'Donovan Michael C, Nakamura Jun, Ozaki Norio, Iwata Nakao

Abstract excerpt

AIMS: Abnormalities in dopaminergic and serotonergic transmission systems are thought to be involved in the pathophysiology of schizophrenia and the mechanisms underlying the therapeutic effects of antipsychotics. We conducted a pharmacogenetic study to evaluate whether variants in dopamine-related genes (DRD1-DRD5, AKT1 and GSK3beta) and serotonin receptor genes (HTR1A, HTR1B, HTR1D, HTR2A, HTR2C, HTR6 and HTR7)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18855532
DOI: 10.2217/14622416.9.10.1437

Genes

AKT1
DRD2
DRD1
DRD5
HTR6
HTR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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