Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term treated HIV infection is associated with platelet mitochondrial dysfunction

18 Mar 2021

Abstract excerpt

Abstract HIV infection and antiretroviral therapy have been linked to mitochondrial dysfunction. The role of platelet mitochondrial dysfunction in thrombosis, immunoregulation and age-related diseases is increasingly appreciated. Here, we studied platelet mitochondrial DNA content (mtDNA pl ) and mitochondrial function in people living with HIV (PLHIV) and related this to platelet function. In a cohort of 208...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV-related health complications and treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33739024
DOI: 10.1038/s41598-021-85775-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term treated HIV infection is associated with platelet mitochondrial dysfunctionPMID 33739024Read ↗

Connection Between HIV and Mitochondria in Cardiovascular Disease and Implications for TreatmentsSemantic proximity Read ↗

Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapiesSemantic proximity Read ↗

Increased platelet–CD8+ T-cell aggregates displaying high activation, exhaustion, and tendency to death correlate with disease progression in people with HIV-1Semantic proximity Read ↗

Elevated Cell-Free Mitochondrial DNA in Filtered Plasma Is Associated With HIV Infection and InflammationSemantic proximity Read ↗

Mitochondrial metabolism as a determinant of heterogeneous platelet functional phenotypes: Implications for antiplatelet resistance.Semantic proximity Read ↗

Anti-HIV Drugs Cause Mitochondrial Dysfunction in Monocyte-Derived MacrophagesSemantic proximity Read ↗

Mitochondrial Toxicity in the Era of HAART: Evaluating Venous Lactate and Peripheral Blood Mitochondrial DNA in HIV-Infected Patients Taking Antiretroviral TherapySemantic proximity Read ↗

HIV Infection and Antiretroviral Therapy Have Divergent Effects on Mitochondria in Adipose TissueSemantic proximity Read ↗

Could mitochondrial DNA quantitation be a surrogate marker for drug mitochondrial toxicity?Semantic proximity Read ↗

Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers.Semantic proximity Read ↗

Plasma extracellular vesicles and cell-free mitochondrial DNA are associated with cognitive dysfunction in treated older adults with HIVSemantic proximity Read ↗

Downregulation of TCF1 in HIV Infection Impairs T-cell Proliferative Capacity by Disrupting Mitochondrial FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.