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Article

Causal association between sleep disorders and nephrolithiasis: a two-sample Mendelian randomization study.

International urology and nephrology - 1 Oct 2026

Huang Lewei, Fan Lianhui, Wang Shudong, Liu Hongtao, Zeng Qingwei, Sun Gang

Abstract excerpt

PURPOSE: Observational evidence indicates an association between sleep disorders and the risk of nephrolithiasis (kidney stones), but whether this relationship reflects a causal effect remains uncertain. The causal relationship between genetically determined sleep disorders and the risk of nephrolithiasis using a two-sample Mendelian randomization (MR) approach was investigated. METHODS: This two-sample MR study...

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Topics

Humans
Mendelian Randomization Analysis
Nephrolithiasis
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Sleep Wake Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Sleep Apnea Syndromes

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Identifiers

PMID: 42026399
DOI: 10.1007/s11255-026-05130-3
PMCID: PMC13585773

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