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Article

Genetic correlation and mendelian randomization reveal the impact of sleep traits on urolithiasis risk.

Scientific reports - 20 Dec 2024

Yan Mo, Zhang Zhe-Xin, Hu Jia-Xin, Wang Kai-Bin, Liu Cheng-Yi

Abstract excerpt

Urolithiasis is a common and recurrent condition in the urological spectrum. Despite various proposed mechanisms, the causal relationship between sleep traits and the risk of urolithiasis remains unclear. We used publicly available genome-wide association study (GWAS) summary data from the UK Biobank and FinnGen to perform a two-sample Mendelian randomization (MR) analysis and genetic correlation analysis,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39706855
DOI: 10.1038/s41598-024-82031-4
PMCID: PMC11662003

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