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Insomnia and sleep duration for kidney function: Mendelian randomization study.

Renal failure - 1 Dec 2024

Zhang Yang, Zhong Zhaozhong, Tang Zuofu, Wang Ruojiao, Wu Jiaqing, Na Ning, Zhang Jinhua

Abstract excerpt

OBJECTIVES: Extensive researches highlight the detrimental impact of sleep disorders such as insomnia and insufficient sleep duration on kidney function. However, establishing a clear causal relationship between insomnia, sleep duration, and kidney function remains challenging. This study aims to estimate this relationship using Mendelian randomization (MR). METHODS: Independent genetic variants strongly...

Topics

Humans
Mendelian Randomization Analysis
Sleep Initiation and Maintenance Disorders
Glomerular Filtration Rate
Genome-Wide Association Study
Creatinine
Sleep
Cystatin C
Kidney
Acute Kidney Injury
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sleep Duration

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Identifiers

PMID: 39132818
DOI: 10.1080/0886022X.2024.2387430
PMCID: PMC11321106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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