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Article

Exploring Bidirectional Causality between Obstructive Sleep Apnea and Chronic Kidney Disease via Mendelian Randomization

1 Jun 2025

Abstract excerpt

Purpose: It remains unclear about the causal association between obstructive sleep apnea (OSA) and chronic kidney disease (CKD) and renal function. This study aimed to explore the bidirectional causal relationship between OSA and CKD and renal function. Methods: We used a 2-sample bidirectional Mendelian randomization (MR) method to evaluate the causal relationship between OSA and estimated glomerular filtration...

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PMID: 40503070
DOI: 10.2147/nss.s503387

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