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Causal association of serum vitamin D levels with urolithiasis: a bidirectional two-sample Mendelian randomization study.

European journal of nutrition - 30 Nov 2024

Zhang Qi-Feng, Zhang He-Zhen, Wang Sheng, Zeng Li-Yuan

Abstract excerpt

BACKGROUND: In light of inconsistent evidence from previous observational studies regarding the correlation between serum vitamin D levels and urolithiasis, this study aimed to investigate the genome-wide causal association between genetically predicted serum 25(OH)D levels and urolithiasis using the Mendelian randomization (MR) approach. METHODS: In this study, we utilized genome-wide association studies (GWAS)...

Topics

Humans
Mendelian Randomization Analysis
Vitamin D
Urolithiasis
Genome-Wide Association Study
Polymorphism, Single Nucleotide
Female

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39614876
DOI: 10.1007/s00394-024-03553-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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