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Article

Causal association between insomnia and diabetic nephropathy independent of diabetes: Evidence from 2-sample Mendelian randomization analysis.

Medicine - 31 Oct 2025

Zhang Jiaxiang, Liu Bin, Han Jiansong, Gu Xinquan

Abstract excerpt

This study investigates the putative causal relationship between insomnia and urinary system diseases utilizing Mendelian randomization (MR) analysis. Instrumental variables were systematically selected based on predefined criteria. Two-sample MR analysis was performed employing the inverse variance weighted method as the primary analytical approach. The causal associations between insomnia and common urological...

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PMID: 41261698
DOI: 10.1097/MD.0000000000045368
PMCID: PMC12582757

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