Article
Antibiotic-Independent Adaptive Effects of Antibiotic Resistance Mutations.
Trends in genetics : TIG - 1 Aug 2017
Hershberg Ruth
Abstract excerpt
Antibiotic usage selects for the accumulation and spread of antibiotic-resistant bacteria. However, resistance can also accumulate in the absence of antibiotic exposure. Antibiotics are often designed to target widely distributed regulatory housekeeping genes. The targeting of such genes enables these antibiotics to be useful against a wider variety of pathogens. This review highlights work suggesting that...
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