Article
The antibiotic resistome: the nexus of chemical and genetic diversity.
Nature reviews. Microbiology - 1 Mar 2007
Wright Gerard D
Abstract excerpt
Over the millennia, microorganisms have evolved evasion strategies to overcome a myriad of chemical and environmental challenges, including antimicrobial drugs. Even before the first clinical use of antibiotics more than 60 years ago, resistant organisms had been isolated. Moreover, the potential problem of the widespread distribution of antibiotic resistant bacteria was recognized by scientists and healthcare...
Topics
- Anti-Bacterial Agents
- Bacteria
- Drug Resistance, Bacterial
- Drug Resistance, Multiple, Bacterial
- Evolution, Molecular
- Gene Transfer, Horizontal
- Genetic Variation
- Humans
- Interspersed Repetitive Sequences
