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Article

Genetic Association of the Renin-Angiotensin-Aldosterone System with hypertension among the Malays and their adaptation to climate change.

PloS one - 1 Jan 2026

Maamor Nur Hasnah, Cengnata Alvin, Pan Yuwen, Rizal Ismail Johan, Abd Malek Khasnur, Williams Gordon H, Yusoff Khalid, Boon-Peng Hoh

Abstract excerpt

Hypertension (HT) is a 'by-product' to the forces of natural selection against environmental drift and salt availability, therefore contributed to differential HT susceptibility. This study provides further supporting evidence through: (i) associating three salt-sensitive related candidate gene variants, to the susceptibility of HT among the Malays from Peninsular Malaysia with a detail genotype-phenotype...

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Share to Angiotensinogen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP11B2

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Share to Receptors, Adrenergic, beta-2

Share to Renin-Angiotensin System

Source

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Identifiers

PMID: 41984970
DOI: 10.1371/journal.pone.0346614
PMCID: PMC13082722

Genes

CYP11B2
ADRB2
AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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