Genetic polymorphisms and hypertension in Indian populations: a systematic review and integrative bioinformatics approach.

doi:10.1186/s12920-026-02437-z

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Article

Genetic polymorphisms and hypertension in Indian populations: a systematic review and integrative bioinformatics approach.

BMC medical genomics - 28 Jul 2026

Sivakumar Rooban, N Prasath, Vijukumar Lakshmi, K A Arul Senghor, P Renuka, V M Vinodhini

Abstract excerpt

BACKGROUND: Hypertension continues to be a major public health issue in India, with increasing incidence associated with both lifestyle factors and genetic susceptibility. Despite genome-wide association studies identifying several loci related with blood pressure worldwide, there is a paucity of integration of these findings within the genetically varied Indian setting. OBJECTIVE: This systematic review aims to...

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Topics

Humans
Hypertension
India
Computational Biology
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease

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PMID: 42919376
DOI: 10.1186/s12920-026-02437-z
PMCID: PMC13692846

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MTHFR

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