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Article

Haplotype analysis of aldosterone synthase gene (CYP11B2) polymorphisms shows association with essential hypertension.

Journal of hypertension - 1 Jul 2003

Kumar Natasha N, Benjafield Adam V, Lin Ruby C, Wang William Y, Stowasser Michael, Morris Brian J

Abstract excerpt

OBJECTIVE: The CYP11B2 locus is an important candidate region in essential hypertension (HT). We therefore investigated CYP11B2 polymorphisms T-344C, T4986C and A6547G for association with essential HT. This included haplotype analysis and measurement of plasma aldosterone levels. METHODS: The three single nucleotide polymorphisms were genotyped by polymerase chain reaction-restriction fragment length...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12817181
DOI: 10.1097/00004872-200307000-00022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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