Article
Blood pressure in patients with primary aldosteronism is influenced by bradykinin B(2) receptor and alpha-adducin gene polymorphisms.
The Journal of clinical endocrinology and metabolism - 1 Jul 2002
Mulatero Paolo, Williams Tracy A, Milan Alberto, Paglieri Cristina, Rabbia Franco, Fallo Francesco, Veglio Franco
Abstract excerpt
Primary aldosteronism (PA) is the most common cause of endocrine hypertension. PA is most frequently presented as moderate to severe hypertension, but the clinical and biochemical features vary widely. The aim of our study was to identify genetic variants that influence the phenotype of patients with PA. We hypothesized that genetic variants potentially affecting aldosterone production (aldosterone synthase,...
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