Article
NetCIS: a network-based common insertion site pipeline for case-control Sleeping Beauty screens.
Briefings in bioinformatics - 1 Mar 2026
Fischbach Mathew J, Reiter Daniel E, Wang Wen, Myers Chad L, Rogers Laura M
Abstract excerpt
Forward genetic screens are powerful tools for novel biological discoveries because they do not require a priori knowledge of genes controlling a phenotype of interest. The Sleeping Beauty (SB) transposon system is one of many commonly employed genetic screen tools used to induce both gain and loss of gene function mutations via insertional mutagenesis. In the past, SB screens have been successfully utilized to...
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