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Distribution of PD-1.5 Gene Variant (rs2227981): A Possible Approach for Risk Assessment in Bladder Cancer.

Archivos espanoles de urologia - 1 Mar 2026

Kayar Kemal, Verim Levent, Sonmez Dilara, Kadihasanoglu Mustafa, Demirkol Seyda, Kucukhuseyin Ozlem, Hakan Mehmet Tolgahan, Lamami Yosra, Kiran Bayram, Yaylim Ilhan

Abstract excerpt

BACKGROUND/AIM: Immune checkpoint pathways are central to tumor immune evasion, and genetic variants of programmed death-1 (PD-1) may influence cancer susceptibility. This study evaluates the association between the PD-1.5 (rs2227981) polymorphism and the risk of bladder cancer (BC) in the Turkish population. MATERIALS AND METHODS: The study included 151 participants, consisting of 53 patients with BC and 98...

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PMID: 41943691
DOI: 10.56434/j.arch.esp.urol.20267902.28

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