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Article

Genetic variants in the death receptor 4 gene contribute to susceptibility to bladder cancer.

Mutation research - 10 Feb 2009

Wang Meilin, Wang Miaomiao, Cheng Gong, Zhang Zhizhong, Fu Guangbo, Zhang Zhengdong

Abstract excerpt

Death receptor 4 (DR4) is an important mediator of apoptosis, and its dysfunction may be related to carcinogenesis and cancer development. We hypothesized that common variants in the DR4 gene are associated with risk of bladder cancer and test this hypothesis in a case-control study of 368 bladder cancer patients and 368 cancer-free controls. We genotyped six tagging single nucleotide polymorphisms (tagSNPs) in...

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Identifiers

PMID: 19070628
DOI: 10.1016/j.mrfmmm.2008.11.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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