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PD-1 rs2227982 Polymorphism Is Associated With the Decreased Risk of Breast Cancer in Northwest Chinese Women: A Hospital-Based Observational Study.

Medicine - 1 May 2016

Ren Hong-Tao, Li Yi-Ming, Wang Xi-Jing, Kang Hua-Feng, Jin Tian-Bo, Ma Xiao-Bin, Liu Xing-Han, Wang Meng, Liu Kang, Xu Peng, Yao Qing-Ling, Dai Zhi-Jun

Abstract excerpt

Programmed death-1 (PD-1) is crucial in cancer and is well characterized as a negative T-cell regulator that functions by delivering inhibitory signals. We aimed to evaluate the relationship between PD-1 polymorphisms (rs10204525, rs2227982, and rs7421861) and breast cancer risk.We selected 560 breast cancer patients and 583 age-, sex-, and ethnicity-matched healthy controls from Northwest China. The PD-1...

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Identifiers

PMID: 27227944
DOI: 10.1097/MD.0000000000003760
PMCID: PMC4902368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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