Article
Programmed Cell Death-1 Polymorphisms Decrease the Cancer Risk: A Meta-Analysis Involving Twelve Case-Control Studies.
PloS one - 1 Jan 2016
Dong Wenjing, Gong Mancheng, Shi Zhirong, Xiao Jianjun, Zhang Junkai, Peng Jiewen
Abstract excerpt
Programmed cell death-1 (PD-1) plays an important inhibitory role in anti-tumor responses, so it is considered as a powerful candidate gene for individual's genetic susceptibility to cancer. Recently, some epidemiological studies have evaluated the association between PD-1 polymorphisms and cancer risk. However, the results of the studies are conflicting. Therefore, a meta-analysis was performed. We identified...
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