Article
Evaluating the Possible Association between PD-1 (Rs11568821, Rs2227981, Rs2227982) and PD-L1 (Rs4143815, Rs2890658) Polymorphisms and Susceptibility to Breast Cancer in a Sample of Southeast Iranian Women.
Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2020
Karami Shima, Sattarifard Hedieh, Kiumarsi Mohammad, Sarabandi Sahel, Taheri Mohsen, Hashemi Mohammad, Bahari Gholamreza, Ghavami Saeid
Abstract excerpt
INTRODUCTION: Programmed cell death-1 (PD-1) and its ligands (PD-L1 and PD-L2) play a critical role as a regulator of immune-system cells, including T cell, natural killer T (NKT), monocytes, dendritic cells (DC), and B cells. OBJECTIVE: This study aimed to find a possible association between PD-1 (rs11568821, rs2227981, rs2227982), and PD-L1 (rs4143815, rs2890658) variants and Breast Cancer (BC) risk in a...