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Article

Association of PD-1 and PDL-1 gene polymorphisms with colorectal cancer risk and prognosis.

Molecular biology reports - 1 Mar 2022

Cevik Mehtap, Namal Esat, Iner-Koksal Ulkuhan, Dinc-Sener Nur, Karaalp Atila, Ciftci Cavlan, Susleyici Belgin

Abstract excerpt

BACKGROUND: Programmed Cell Death-1 (PD-1) together with Programmed Death Ligand 1 (PDL-1) have crucial roles in anti-tumor immune response, cancer susceptibility and prognosis. Since PD-1 and PDL-1 have been considered as important genetic risk factors in cancer development and their functions can be affected by polymorphic sites, we investigated the effects of PD-1 rs2227981, rs2227982, rs36084323 and PDL-1...

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Identifiers

PMID: 35076848
DOI: 10.1007/s11033-021-06992-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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