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Article

Cysteine cathepsins and autoimmune diseases: A bidirectional Mendelian randomization.

Medicine - 25 Oct 2024

Wu Yetong, Li Qiaoqiao, Lou Yake, Zhou Zhongzheng, Huang Jing

Abstract excerpt

Cysteine cathepsins are proteolytic enzymes crucial in various physiological and pathological processes, primarily operating within lysosomes. Their functions include protein degradation, immune system regulation, and involvement in various diseases. While some cysteine cathepsins play important roles in the immune system, their connection to autoimmune diseases remains unclear. This study proposes using...

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Autoimmune Diseases
Cathepsin B
Cathepsins
Colitis, Ulcerative
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39470488
DOI: 10.1097/MD.0000000000040268
PMCID: PMC11521024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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