Article
Analysis of the rs3807135, rs3757385 and rs3778754 Variants of the IRF5 Gene and mRNA Expression in Patients with Melanoma Cancer from Western Mexico.
Genes - 24 Feb 2026
Tapia-Leyva Claudia A, Valdez-Salazar Fernando, Jiménez-Del Río Luis A, Padilla-Gutiérrez Jorge R, Muñoz-Valle José F, Valdés-Alvarado Emmanuel
Abstract excerpt
OBJECTIVE: To analyze the association between the IRF5 gene variants rs3807135, rs3757385, and rs3778754 and mRNA expression levels in patients from western Mexico diagnosed with melanoma. METHODS: An analytical cross-sectional study was conducted including 374 individuals (153 patients with newly diagnosed melanoma and no previous treatment, and 221 controls). The melanoma group was matched to the reference...
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