Article
Involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma.
PloS one - 1 Jan 2014
Arroyo-Berdugo Yoana, Alonso Santos, Ribas Gloría, Ibarrola-Villava Maider, Peña-Chilet María, Martínez-Cadenas Conrado, Gardeazabal Jesús, Ratón-Nieto Juan Antonio, Sánchez-Díez Ana, Careaga Jesús María, Pérez-Yarza Gorka, Carretero Gregorio, Martín-González Manuel, Gómez-Fernández Cristina, Nagore Eduardo, Asumendi Aintzane, Boyano María Dolores
Abstract excerpt
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic traits. Several low penetrance susceptibility genes associated with malignant melanoma (MM) have been described, including genes related to pigmentation, DNA damage repair and oxidative stress...
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