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Article

IRF5 gene polymorphisms in melanoma.

Journal of translational medicine - 21 Aug 2012

Uccellini Lorenzo, De Giorgi Valeria, Zhao Yingdong, Tumaini Barbara, Erdenebileg Narnygerel, Dudley Mark E, Tomei Sara, Bedognetti Davide, Ascierto Maria Libera, Liu Qiuzhen, Simon Richard, Kottyan Leah, Kaufman Kenneth M, Harley John B, Wang Ena, Rosenberg Steven A, Marincola Francesco M

Abstract excerpt

BACKGROUND: Interferon regulatory factor (IRF)-5 is a transcription factor involved in type I interferon signaling whose germ line variants have been associated with autoimmune pathogenesis. Since relationships have been observed between development of autoimmunity and responsiveness of melanoma...

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Identifiers

PMID: 22909381
DOI: 10.1186/1479-5876-10-170
PMCID: PMC3492128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22909381-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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