Article
CDKN2A Polymorphism in Melanoma Patients in Colombian Population: A Case-Control Study.
BioMed research international - 1 Jan 2020
Tovar-Parra Jose D, Gutiérrez-Castañeda Luz D, Gil-Quiñones Sebastián R, Nova Jhon A, Pulido Leonardo
Abstract excerpt
INTRODUCTION: Melanoma is the most aggressive type of skin cancer, with poor prognosis in advanced stages. The incidence and mortality rates have increased in recent years. Single nucleotide polymorphisms p.R24P, p.M53I, p.G101W, p.V126D, and p.A148T in the CDKN2A (HGNC ID: 1787) gene have been associated with the development of melanoma in different populations; however, this association has not been studied in...
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