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Relationships between Lipid-Related Metabolites and Age-Related Macular Degeneration Vary with Complement Genotype

12 Aug 2022

Abstract excerpt

Objective: Lipid dysregulation and complement system (CS) activation are 2 important pathophysiology pathways for age-related macular degeneration (AMD). We hypothesized that the relationship between lipids and AMD may also differ according to CS genotype profile. Thus, the objective was to investigate the relationships between lipid-related metabolites and AMD according to CS genotypes. Design: Population-based...

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PMID: 36531576
DOI: 10.1016/j.xops.2022.100211

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