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Article

Identification of a genetic locus responsible for the dominant white-spotting coat phenotype in mice spontaneously isolated from a Japanese wild-derived inbred strain.

The Journal of veterinary medical science - 1 May 2026

Ochiai Hiromitsu, Takahashi Gou, Ishida Yuki, Matsushima Yoshibumi, Wada Kenta

Abstract excerpt

Agouti-dominant spotting (Ads) is a novel mutant mouse that was spontaneously isolated from KOR1/Stm (KOR1), an inbred strain derived from a Japanese wild mouse. Heterozygous Ads mice exhibit dominant white-spotting on the dorsal coat, whereas homozygous mice display embryonic lethality. We generated [Ads×C57BL/6J (B6)]F1 (F1), F2 and [B6×(Ads×B6)]N2 (N2) mice to investigate the inheritance patterns of the Ads...

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Identifiers

PMID: 41882906
DOI: 10.1292/jvms.25-0443
PMCID: PMC13183506

Genes

F2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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