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Article

A new coat color mouse line for testing germline transmission of embryonic stem cells while retaining an inbred genetic background.

Journal of the American Association for Laboratory Animal Science : JAALAS - 1 May 2007

Barbaric Ivana, Stewart Michelle, Wells Sara, Dear T Neil

Abstract excerpt

Most gene-targeted mice are produced on a mixed genetic background of C57BL/6 and substrains of 129/Sv. Mating chimeric mice containing 129/Sv-derived embryonic stem cells that are wild type at the agouti locus (A) in a nonagouti (a) donor genetic background with inbred C57BL/6 mice that are homozygous for the nonagouti allele allows the use of coat color to detect germline transmission. Agouti pups from such a...

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PMID: 17487951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A new coat color mouse line for testing germline transmission of embryonic stem cells while retaining an inbred genetic background.PMID 17487951Read ↗

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