Article
New semidominant mutations that affect mouse development.
Genesis (New York, N.Y. : 2000) - 1 Oct 2004
Bogani Debora, Warr Nick, Elms Paul, Davies Jennifer, Tymowska-Lalanne Zuzanna, Goldsworthy Michelle, Cox Roger D, Keays David A, Flint Jonathan, Wilson Valerie, Nolan Pat, Arkell Ruth
Abstract excerpt
Dominantly acting mutations that produce visible phenotypes are frequently recovered, either during routine maintenance of colonies or from mutagenesis experiments. We have studied 12 dominant mouse mutations that cause a tail dysmorphology, a coat spotting phenotype, or a combination of these. The majority of these mutations act in a semidominant manner with the homozygous state associated with embryonic...
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