New semidominant mutations that affect mouse development.

doi:10.1002/gene.20071

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Article

New semidominant mutations that affect mouse development.

Genesis (New York, N.Y. : 2000) - 1 Oct 2004

Bogani Debora, Warr Nick, Elms Paul, Davies Jennifer, Tymowska-Lalanne Zuzanna, Goldsworthy Michelle, Cox Roger D, Keays David A, Flint Jonathan, Wilson Valerie, Nolan Pat, Arkell Ruth

Abstract excerpt

Dominantly acting mutations that produce visible phenotypes are frequently recovered, either during routine maintenance of colonies or from mutagenesis experiments. We have studied 12 dominant mouse mutations that cause a tail dysmorphology, a coat spotting phenotype, or a combination of these. The majority of these mutations act in a semidominant manner with the homozygous state associated with embryonic...

Topics

Alkylating Agents
Animals
Animals, Congenic
Biomarkers
Chromosome Mapping
Embryonic Development
Ethylnitrosourea
Female
Genes, Dominant
Genes, Lethal
Genetic Markers
Genome
Hair Color
Haplotypes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homozygote

Male

Mice

Mice, Inbred BALB C

Source

Open in PubMed

Identifiers

PMID: 15384171
DOI: 10.1002/gene.20071

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