Mouse coat color mutations: from fancy mice to functional genomics.

doi:10.1002/dvdy.20840

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Article

Mouse coat color mutations: from fancy mice to functional genomics.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2006

Steingrímsson Eiríkur, Copeland Neal G, Jenkins Nancy A

Abstract excerpt

Mouse coat color mutations have a long history in biomedical research. The viable and visible phenotype of most coat color mutations has made the pigment cell, the melanocyte, an ideal system for genetic, molecular, and cellular analysis. Molecular cloning and analysis of many of the different coat color mutations have revealed the roles of a diverse range of genes, and today we know more about the pathways and...

Topics

Animals
Cell Differentiation
Genomics
Hair Color
Melanocytes
Melanosomes
Mice
Mutation
Pigments, Biological
Skin Pigmentation
Stem Cells

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Open in PubMed

Identifiers

PMID: 16691561
DOI: 10.1002/dvdy.20840

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