Article
Non-Host Factors Influencing Onset and Severity of Celiac Disease.
Gastroenterology - 1 Jun 2024
Galipeau Heather J, Hinterleitner Reinhard, Leonard Maureen M, Caminero Alberto
Abstract excerpt
Celiac disease (CeD) is a chronic autoimmune condition driven by gluten ingestion in genetically predisposed individuals, resulting in inflammatory lesions in the proximal small intestine. Although the presence of specific HLA-linked haplotypes and gluten consumption are necessary for disease development, they alone do not account for the variable onset of CeD in susceptible individuals. This review explores the...
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