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Immunopathogenesis and environmental triggers in coeliac disease

25 Jul 2022

Abstract excerpt

Coeliac disease (CD) is a frequent immune enteropathy induced by gluten in genetically predisposed individuals. Its pathogenesis has been extensively studied and CD has emerged as a model disease to decipher how the interplay between environmental and genetic factors can predispose to autoimmunity and promote lymphomagenesis. The keystone event is the activation of a gluten-specific immune response that is driven...

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PMID: 35879049
DOI: 10.1136/gutjnl-2021-326257

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