Article
Frontiers in Celiac Disease: Where Autoimmunity and Environment Meet.
The American journal of surgical pathology - 1 Jan 2022
Patel Natalie, Robert Marie E
Abstract excerpt
Celiac disease is a chronic, immune-mediated enteropathy driven by dietary gluten found in genetically susceptible hosts. It has a worldwide distribution, is one of the most common autoimmune disorders globally, and is the only autoimmune condition for which the trigger is known. Despite advances in characterizing mechanisms of disease, gaps in understanding of celiac disease pathogenesis remain. A "frontier"...
Topics
- Animals
- Autoimmunity
- Bacteria
- Biopsy
- Celiac Disease
- Duodenum
- Dysbiosis
- Environment
- Gastrointestinal Microbiome
- Host-Pathogen Interactions
- Humans
- Phenotype
