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Article

A genetic study of immunity in depression and interactions with childhood maltreatment.

Translational psychiatry - 19 Mar 2026

Herrera-Rivero Marisol, McCartney Daniel L, Whalley Heather C, Berger Klaus, McIntosh Andrew M, Baune Bernhard T

Abstract excerpt

Genetic and environmental factors contribute to depression. Among the latter, early life adversity and immune dysregulation have been consistently linked with depression. Childhood maltreatment (CM) is believed to induce immune dysregulation later in life. However, it is not known how CM might interact with genetic immune factors to contribute to the occurrence of depression. We investigated how genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41856978
DOI: 10.1038/s41398-026-03935-5
PMCID: PMC13039853

Genes

GHR
RUNX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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